Defining fluoropolymer surfaces for enhanced nerve cell interaction. by Yen Wah Tong

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Pagination1 v. (in various foliations).
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Open LibraryOL19768919M
ISBN 100612498344

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Surfaces with a single peptide showed significantly lesser response. The specificity of the cell-peptide interaction was demonstrated with a cornpetitive assay.

These well-defined fluoropolymer surfaces confirmed that nerve cell interaction was enhanced by the coupling of. Embryonic hippocampal neurons cultured on surface modified fluoropolymers showed enhanced interaction and neurite extension.

Poly(tetrafluoroethylene-co-hexafluoropropylene) (FEP) film. Fluoropolymers continue to enable new materials and technologies as a result of their remarkable properties. This book reviews fluoropolymer platforms of established commercial interest, as well as recently discovered methods for the preparation and processing of new fluorinated materials.

It covers the research and development of fluoropolymer synthesis, characterization, and. Electrical signal is one of the most important elctrophysiological phenomena and is widely used in electrogensis and electrodiagnosis.

The use of appropriate external electrical stimulation (ES) to in situ modify cellular behavior can desirably promote tissue regeneration. Considering its high electron mobility and surface area, graphene could become a promising Cited by: The possibility of modifying surfaces, both chemically and physically, permits the manufacturing of platforms to control regeneration-competent cell behaviour, either for cell transplant, ex vivo cultures on substrates, or for in situ action (Silva, ).

More particularly, it has been shown that NPC, Schwann cells and astrocytes Cited by: 1. The capability to graft synthetic polymers onto the surfaces of live cells offers the potential to manipulate and control their phenotype and underlying cellular processes.

Conventional grafting Cited by: Dennis W. Smith Jr. is a Professor of Chemistry at The University of Texas at Dallas, Texas. Previously, he was at The Dow Chemical Company Central Research Laboratory and worked in synthesis and characterization.

His research interests include synthesis, mechanism, structure/property relationships, and applications of polymer materials and : Wiley. The enhanced therapeutic selectivity was confirmed by 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) tests and trypan blue exclusion tests of.

1. Introduction. Central nerve injuries generally lead to dysfunction and loss of neuronal tissue, resulting in long-term disabilities and major socio-economic costs. 1,2 The multipotent property of neural stem cells (NSCs), which can differentiate into neurons and glial cells, suggests that these cells are promising candidates for the treatment of Cited by: The tests revealed a correlation Defining fluoropolymer surfaces for enhanced nerve cell interaction.

book the activity with the Co/(Co + Mo) ratio having a maximum at ~-~ We attribute the Co LIIIA peak to cobalt reduced and sulfided by the H2/H2S treatment and the Co Lss peak to CoAl2O~ formed by interaction of the dispersed phase with the support during by:   INTRODUCTION.

Solid supports have been used as platforms for the photorelease of drug molecules. 1,2 However, there are gaps in data on whether Teflon-like 3,4 or superhydrophobic surfaces 5 can efficiently photorelease drugs. To address this issue, two photoactive fluoropolymers have been synthesized and compared (Figure 1).One is made of Cited by: The structural biology of membrane proteins has become an important focus of recent biochemical research.

With at least 30% of the human genome encoding for membrane proteins, they play a vital role in cell communication and most biological functions, yet their detailed structures remain poorly characterized. The efficacy of tetrodotoxin (TTX), a very potent local anesthetic, is limited by its poor penetration through barriers to axonal surfaces.

To address this issue, we encapsulated TTX in hollow silica nanoparticles (TTX-HSN) and injected them at the sciatic nerve in rats. TTX-HSN achieved an increased frequency of successful blocks, prolonged the duration of the block, Cited by: 3. The toxic effects of Ag nanoparticles (NPs) remain an issue of debate, where the respective contribution of the NPs themselves and of free Ag+ ions present in the NP stock suspensions and after intracellular NP corrosion are not fully understood.

Here, we employ a recently set up methodology based on high-content (HC) imaging combined with high-content gene Cited by: A water soluble polythiophene with tyrosine kinase inhibitor lapatinib as side chain moieties (PTL) was designed and synthesized.

Together with its fluorescent characteristic and low cytotoxicity, PTL can be used for cell membrane imaging of living cells by targeting the intracellular domain of transmembrane protei Conjugated polymersCited by: (Book Review) [ChemBioChem] M.

O’Malley, M. Helgeson, N. Wagner, A. Robinson, “Toward rational design of protein detergent complexes: determinants of mixed micelles that are critical for the in vitro stabilization of a G-protein coupled receptor,” Biophysical Journal, (8): ().

Cell and Molecular Response to Stress Vol. 3 - Sensing, Signaling and Cell Adaptation (Elsevier) Cell and Tissue Based Molecular Pathology (Elsevier) Cell Biology (Third Edition) (Elsevier) Cell Lineage and Fate Determination (Elsevier) Cell Physiology Source Book (Fourth Edition) (Elsevier)   Tong YW, Shoichet MS.

Enhancing the neuronal interaction on fluoropolymer surfaces with mixed peptides or spacer group linkers. Biomaterials. ;22(10)– PubMed CrossRef Google ScholarCited by: 2. ARTICLES Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles AYUSH VERMA1, OKTAY UZUN1, YUHUA HU2, YING HU1, HEE-SUN HAN3, NICKI WATSON4, SUELIN CHEN1, DARRELL J.

IRVINE1,5* AND FRANCESCO STELLACCI1* 1Department of Materials Science and Engineering, MIT, MassachusettsUSA. In this paper, we demonstrate a designed and synthesized triazinedithiolsilane molecule - 6-(3-triethoxysilylpropyl) amino-1,3,5-triazine-2,4-dithiol monosodium salt (abbre-viation, TESPA, see Figure 1) according to the strategies mentioned.

TESPA has three active sites which refer to two mercapto groups [21] and a nitrogen atom. We alsoCited by: Immobilization of Polymeric Luminophor on Nanoparticles Surface Yuliia Bolbukh1*, Beata Podkoscielna2, Agnieszka Lipke2, Andrzej Bartnicki2, Barbara Gawdzik2 and Valentin Tertykh1 Abstract Polymeric luminophors with reduced toxicity are of the priorities in the production of lighting devices, sensors, detectors, bioassays or diagnostic by: 1.

Surface-structure-regulated penetration of nanoparticles across cell membrane Electronic Supplementary Information Yinfeng Li,a,b cXuejin Li, bZhonghua Lia and Huajian Gao* aDepartment of Engineering Mechanics, Shanghai Jiao Tong University, ShanghaiChina. bSchool of Engineering, Brown University, Providence, Rhode IslandUSA.

nal ganglion cell axons for DM-GRASP-coated micro-lanes requires clathrin-mediated endocytosis for the appropriate axonal turning reactions at substrate borders.

A major limitation of cell therapies is the rapid decline in viability and function of the transplanted cells. Here we describe a strategy to enhance cell therapy via the conjugation of adjuvant drug–loaded nanoparticles to the surfaces of therapeutic cells.

With. apparent nerve regeneration were re-anaesthetized and the sciatic nerve was exposed. The stimulating cathode was a stainless-steel monopolar needle, which was placed directly on the sciatic nerve trunk, 5 mm proximal to the transection site. The anode was another stainless-steel monopolar needle placed 3 mm proximal to the cathode.

Bio-interface of conducting polymer-based materials for neuroregeneration Abstract Nerve system diseases like Parkinson's disease, Huntington's disease, Alzheimer's disease, etc. seriously affect thousands of patients' lives every year, making them suffer from.

We report a one-step synthesis protocol for obtaining polymer-coated magnetic nanoparticles (MNPs) engineered for uploading neural cells.

Polyethyleneimine-coated Fe 3 O 4 nanoparticles (PEI-MNPs) with sizes of 25 ± 5 nm were prepared by oxidation of Fe(OH) 2 by nitrate in basic aqueous media and adding PEI in situ during synthesis. The obtained PEI-MNP cores.

A group of scientists from the National University of Singapore published a study in the May 30th issue of Nanotechnology, which developed polymer nanofiber membranes with a synthesized catalyst.

ification of polymer surfaces is rapidly growing and the method has gained considerable interest among scien-tists in the past decade. Several experiments and studies have been carried out by using a laser to alter the sur-face property of materials. Interaction of UV laser pulses with polymers and biological tissues led to a discovery.

ASJC Scopus subject areas. Surfaces, Coatings and Films; Electronic, Optical and Magnetic Materials; Biomaterials; Colloid and Surface ChemistryCited by: Tubular nerve guidance channels were extruded from a vinylidenefluoride-trifluoroethylene copolymer using a melt-extrusion process.

Unlike vinylidenefluoride homopolymer, the copolymer does not need mechanical stretching to achieve a dipole-containing crystal structure, enabling the fabrication of complex piezoelectric devices. • Enhanced dark-field imaging techniques to detect individual nanoparticles in tissue sections.

• Examine distribution and re-distribution of inhaled MWCNTs in the lungs by methods that enhance detection of single nanoparticles. • Determine the lung’s fibrotic response to MWCNT. Silk Fibroin Based Porous Materials Qiang Zhang, Shuqin Yan and Mingzhong Li * defining the 3D geometry for the tissue to be engineered, the scaffold provides the microenvironment net is highly human cell-compatible and may be applicable File Size: KB.

HT – 29 human colon adenocarcinoma cell line (American Type Culture Collection) was used as cellular model in this study and the interaction with nanoparticles was investigated.

Biography: Catalin Zaharia is Professor of Polymer Science at University Politehnica of Bucharest and Project Team Leader in Advanced Polymer Material Group. The cytotoxic effects of lipidic formulated gold porphyrin nanoparticles for the treatment of neuroblastoma Puiyan Lee1, Yifan Zhu1, Jessie J Yan2, Raymond WY Sun2, Wei Hao1, Xuelai Liu1, Chi-Ming Che2, Kenneth KY Wong11Department of Surgery, Li Ka Shing Faculty of Medicine, 2Department of Chemistry and Open Laboratory of Chemical Biology of the Institute.

tendon, skin and nerve) (Pham). The surface properties (i.e. wettability, surface chemistry) of these engineered nanofibrous scaffolds play an important role in being successful in tissue engineering applications as they strongly affect cell–extracellular matrix interactions (Mrksich, ). Unfortunately, most of theAuthor: Mahtab Asadian, Heidi Declercq, Maria Cornelissen, Rino Morent, Nathalie De Geyter.

Interfacial charge transfer (ICT) across the molecule-TiO2 nanoparticle interface has gained enormous research attention for applications in dye sensitized solar cells (DSSC), photo-catalysis, water splitting and nonlinear optics.

DSSCs are promising clean alternative energy sources. However, current DSSCs suffer from lower efficiencies and higher : Edwin Mghanga. Interaction of ulva and navicula marine algae with surfaces of pyridinium polymers with fluorinated side-chains. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) (), 46(2), Published Papers “Feasibility of laparoscopic abdominal wall reconstruction in an outpatient community-hospital setting using cPTFE prosthetic mesh: a prospective, multicenter case series” T.

Unruh, J. Adjei Boachie, E. Smith-Singares- Chicago, IL. Ab-mediated cell‒NP interactions 50 Immunotherapeutic potential of Ab-functionalized UnTHCPSi NPs 52 Drug release and anticancer effect 54 Surface polymeric engineering of the PSi NPs for the cellular interaction enhancement (IV and V) 56 Stability, cellular association and endosomal escape 56Author: Mohammad-Ali Shahbazi.

Author(s): Adeleye, Adeyemi S; Conway, Jon R; Perez, Thomas; Rutten, Paige; Keller, Arturo A | Abstract: The influence of phytoplankton-derived soluble extracellular polymeric substances (EPS), pH, and ionic strength (IS) on the dissolution, speciation, and stability of nano-CuO, nano-Cu, and Kocide (a micron sized Cu(OH)2-based fungicide) was investigated over 90 days.

Cited by: Full text of "Personal Protective Equipment For Chemical, Biological, And Radiological Hazards Design, Evaluation, And Selection" See other formats.Atomic polarization and local reactivity on organic ferroelectric surfaces: Engineering fluoropolymer films for ferroelectric nanolithography, DEFINING A T CELL-INTRINSIC ROLE FOR MYD88 DURING LCMV INFECTION, MONITORING OF IMMUNE CELL RESPONSE TO B CELL DEPLETION THERAPY AND NERVE ROOT INJURY USING SPIO ENHANCED .

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